BENIDIPINE HCL
We are offering
high quality of BENIDIPINE. We are known for manufacturing, exporting,
distributing, trading and supplying Benidipine Hydrochloride in Ankleshwar,
Gujarat, India. Further, this is safely packaged by our professionals in
diverse packaging options that maintain its purity and effectiveness. BENIDIPINE
is available at dose of 4 mg and 8 mg. BENIDIPINE having minimum of
side effect as compare to other antihypertensive drugs.
BENIDIPINE is
a new generation triple L-, T-, and N- type calcium channel blocker used as
antihypertensive agent. It is reno protective and cardio protective which is
found to be superior to Cilnidipine and Amlodipine as per
clinical studies.
Niksan Pharmaceutical is leading Manufacturer, Exporter,
Distributor, and Supplier of BENIDIPINE in
Ankleshwar, Gujarat, India. Niksan Pharmaceutical manufacturing all products under
GMP site.
After DPCO-2013,
348 Drugs are now under DPCO and
Amlodipine is one of them.
After DPCO-2014,
Cilnidipine is now also under DPCO.
So, All the Pharmaceutical
Formulation Company Searching alternative for Amlodipine and Cilnidipine. BENIDIPINE is the best option of Cilnidipine
and Amlodipine.
Amlodipine is a new
generation L-type Calcium channel blocker used as antihypertensive agent
Cilnidipine is a new
generation N-type Calcium channel blocker used as antihypertensive agent
BENIDIPINE ADVANTAGES OVER AMLODIPINE AND CILNIDIPINE
Ø
One of the main
advantages of BENIDIPINE is less dosage
compare to Amlodipine and Cilnidipine.
Ø
BENIDIPINE is a new generation triple L-,
T-, and N- type calcium channel blocker used as antihypertensive agent.
Ø
Benidipine exerted an antiproteinuric effect to
a greater extent than cilnidipine in patients with diabetes.
Ø
Benidipine exerted more protective effects
against cardiorenal injury of hypertensive rats than cilnidipine, through more
attenuation of oxidative stress than cilnidipine, and the reduction of
aldosterone. Benidipine, via blockade of T-type calcium channels, seems to
elicit additive benefits for prevention of hypertensive cardiorenal injury.
SPECIFICATION
|
Tests
|
Requirements
|
Results
|
|
Physical appearance
|
Yellowish or yellow crystalline
powder
|
Confirmed
|
|
Solubility
|
Very Soluble in Formic acid Soluble
in Methanol, Slightly soluble in ethanol (99.5) and practically insoluble in
water
|
Confirmed
|
|
Identification by IR
|
IR absorption of the sample must
be concordant with the standard spectrum.
|
Confirmed
|
|
Melting Point
|
105°-110°C
|
107°-109°C
|
|
Loss on drying
|
Not more than 0.50% w/w
|
0.02%w/w
|
|
Residue after Ignition
|
Not more than 0.20% w/w
|
0.07%w/w
|
|
Heavy metals
|
Not more than 10 ppm
|
Less than 10 ppm
|
|
Related substances(by HPLC)
Individual impurity
Total impurities
|
Not more than 0.5%
Not more than 1.0%
|
0.20%
0.28%
|
|
Assay (on dried base)
|
Between 99.0% to 101.0%
|
99.4%w/w
|
|
Conclusion
|
The material complies with
respect to the above specification
|
|
ADDITIONAL
INFORMATION
|
CAS No.
|
105979-17-7
|
|
Min. Order Quantity
|
1 Kilogram
|
|
Port
|
NhavaSheva By Sea and Sahar
Airport By Air
|
|
Freight
|
To Pay basis
|
|
Insurance
|
Your Account
|
|
Payment Terms
|
L/C, T/T
|
|
Delivery Time
|
Immediates
|
|
Packaging Details
|
HDPE drum with inner LPDE liners
|
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