BENIDIPINE HCL MANUFACTURER

BENIDIPINE HCL

We are offering high quality of BENIDIPINE. We are known for manufacturing, exporting, distributing, trading and supplying Benidipine Hydrochloride in Ankleshwar, Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness. BENIDIPINE is available at dose of 4 mg and 8 mg. BENIDIPINE having minimum of side effect as compare to other antihypertensive drugs.

BENIDIPINE is a new generation triple L-, T-, and N- type calcium channel blocker used as antihypertensive agent. It is reno protective and cardio protective which is found to be superior to Cilnidipine and Amlodipine as per clinical studies. 

Niksan Pharmaceutical is leading Manufacturer, Exporter, Distributor, and Supplier of BENIDIPINE in Ankleshwar, Gujarat, India. Niksan Pharmaceutical manufacturing all products under GMP site.

After DPCO-2013, 

348 Drugs are now under DPCO and Amlodipine is one of them.

After DPCO-2014, 

Cilnidipine is now also under DPCO.

So, All the Pharmaceutical Formulation Company Searching alternative for Amlodipine and Cilnidipine.  BENIDIPINE is the best option of Cilnidipine and Amlodipine. 

Amlodipine is a new generation L-type Calcium channel blocker used as antihypertensive agent

Cilnidipine is a new generation N-type Calcium channel blocker used as antihypertensive agent

BENIDIPINE ADVANTAGES OVER AMLODIPINE AND CILNIDIPINE

Ø  One of the main advantages of BENIDIPINE is less dosage compare to Amlodipine and Cilnidipine.

Ø  BENIDIPINE is a new generation triple L-, T-, and N- type calcium channel blocker used as antihypertensive agent.

Ø  Benidipine exerted an antiproteinuric effect to a greater extent than cilnidipine in patients with diabetes.

Ø  Benidipine exerted more protective effects against cardiorenal injury of hypertensive rats than cilnidipine, through more attenuation of oxidative stress than cilnidipine, and the reduction of aldosterone. Benidipine, via blockade of T-type calcium channels, seems to elicit additive benefits for prevention of hypertensive cardiorenal injury.

                    

SPECIFICATION

Tests	Requirements	Results
Physical appearance	Yellowish or yellow crystalline powder	Confirmed
Solubility	Very Soluble in Formic acid Soluble in Methanol, Slightly soluble in ethanol (99.5) and practically insoluble in water	Confirmed
Identification by IR	IR absorption of the sample must be concordant with the standard spectrum.	Confirmed
Melting Point	105°-110°C	107°-109°C
Loss on drying	Not more than 0.50% w/w	0.02%w/w
Residue after Ignition	Not more than 0.20% w/w	0.07%w/w
Heavy metals	Not more than 10 ppm	Less than 10 ppm
Related substances(by    HPLC) Individual impurity Total impurities	Not more than 0.5% Not more than 1.0%	0.20% 0.28%
Assay (on dried base)	Between 99.0% to 101.0%	99.4%w/w
Conclusion	The material complies with respect to the above specification

ADDITIONAL INFORMATION

CAS No.	105979-17-7
Min. Order Quantity	1 Kilogram
Port	NhavaSheva By Sea and Sahar Airport By Air
Freight	To Pay basis
Insurance	Your Account
Payment Terms	L/C, T/T
Delivery Time	Immediates
Packaging Details	HDPE drum with inner LPDE liners

 (Product projected by valid patents are not offered for sale in countries where such patents are still valid and its liability is at Buyers Risk)