http://www.niksanpharmaceutical.in/cilnidipine.htm
Cilnidipine
We are leading Manufacturer, Exporter, Distributor,
and Supplier of Cilnidipine in Ankleshwar, Gujarat, India. To understand the
largest accomplishment of clients, we present these ranges at very realistic
price ranges. It finds its
applications in hospitals, medical stores and clinics. Cilnidipine
is processed using the quality approved chemical substances in a very hygienic
environment under the proper observation of our dexterous team. Cilnidipine
tablets manufacture contact us for best rate of Bulk Drugs. Niksan
Pharmaceutical is leading Manufacturer, Exporter, Distributor, and Supplier of
Cilnidipine in Ankleshwar, Gujarat, India. Niksan Pharmaceutical manufacturing
all products under GMP Facility.
Cilnidipine is a new generation N-type Calcium channel blocker
used as antihypertensive agent and found to be superior to amlodipine as per clinical
studies.
CILNIDIPINE ADVANTAGES OVER AMLODIPINE
Ø One of the main
advantage of CILNIDIPINE is it REDUCES THE
INCIDENCE OF PEDAL EDEMA UNLIKE AMLODIPINE
Ø L-type calcium
channel blocker (Amlodipine) dilates the only arterioles & not the venules,
hence blood pressure increases in the capillary bed and are thought to cause
leg edema.
After DPCO-2013,
348 Drugs are now under DPCO and Amlodipine is one of them,
So, All the Pharmaceutical Formulation Company
Searching alternative for Amlodipine, and Cilnidipine is best option of Amlodipine.
Cilnidipine Approved by CDSCO or
DCGI on 21-06-2007
Cilnidipine have compatibility with other API
like Telmisartan, Olmesartan Medoxomil, Ramipril and Metoprolol
Succinate as it found in combination formulation in Indian markets are as
follow.
Cilnidipine 5 mg Tablet
Cilnidipine 10 mg Tablet
Cilnidipine 20 mg Tablet
Cilnidipine 5 mg + Telmisartan 20 mg Tablet
Cilnidipine10 mg + Telmisartan 40 mg Tablet
Cilnidipine 5 mg + Telmisartan 20 mg Tablet
Cilnidipine10 mg + Telmisartan 40 mg Tablet
Cilnidipine 10 mg + Metoprolol Succinate 25 mg
Tablet
Cilnidipine 10 mg + Metoprolol Succinate 50 mg Tablet
Cilnidipine 10 mg + Metoprolol Succinate 50 mg Tablet
Cilnidipine 10 mg + Olmesartan Medoxomil 20 mg Tablet
Cilnidipine 10 mg + Olmesartan Medoxomil 40 mg Tablet
Cilnidipine 10 mg + Ramipril IP 10 mg Capsule
Cilnidipine 10 mg + Ramipril IP 2.5 mg Capsule
Cilnidipine 5 mg + Hydrochlorothiazide
12.5 mg + Telmisartan 40 mg
ADDITIONAL INFORMATION
CAS No.
|
132203-70-4
|
Min. Order
Quantity
|
1 Kilogram
|
Port
|
NhavaSheva
By Sea and Sahar Airport By Air
|
Freight
|
To Pay basis
|
Insurance
|
Your Account
|
Payment
Terms
|
L/C, T/T
|
Delivery
Time
|
Immediates
|
Packaging
Details
|
HDPE drum
with inner LPDE liners
|
SPECIFICATION
Tests
|
Requirements
|
Results
|
Physical appearance
|
Yellowish
or yellow powder
|
Confirmed
|
Solubility
|
Soluble in
Dimethyl sulphoxide, Practically insoluble in water, Slightly soluble in
anhydrous ethanol
|
Confirmed
|
Identification by IR
|
IR
absorption of the sample must be concordant with the standard spectrum.
|
Confirmed
|
Melting Point
|
105°-110°C
|
107°-109°C
|
Loss on
drying
|
Not more
than 0.50% w/w
|
0.02%w/w
|
Residue
after Ignition
|
Not more
than 0.20% w/w
|
0.07%w/w
|
Heavy
metals
|
Not more
than 10 ppm
|
Less than
10 ppm
|
Related substances(by HPLC)
Individual
impurity
Total
impurities
|
Not more
than 0.5%
Not more
than 1.0%
|
0.20%
0.28%
|
Assay (on
dried base)
|
Not less
than 98.5%
|
99.4%w/w
|
Conclusion
|
The
material complies with respect to the above specification
|
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