Tuesday, 12 March 2019

CILNIDIPINE MANUFACTURER IN INDIA







http://www.niksanpharmaceutical.in/cilnidipine.htm

Cilnidipine

We are leading Manufacturer, Exporter, Distributor, and Supplier of Cilnidipine in Ankleshwar, Gujarat, India. To understand the largest accomplishment of clients, we present these ranges at very realistic price ranges. It finds its applications in hospitals, medical stores and clinics. Cilnidipine is processed using the quality approved chemical substances in a very hygienic environment under the proper observation of our dexterous team. Cilnidipine tablets manufacture contact us for best rate of Bulk Drugs. Niksan Pharmaceutical is leading Manufacturer, Exporter, Distributor, and Supplier of Cilnidipine in Ankleshwar, Gujarat, India. Niksan Pharmaceutical manufacturing all products under GMP Facility.

Cilnidipine is a new generation N-type Calcium channel blocker used as antihypertensive agent and found to be superior to amlodipine as per clinical studies. 

CILNIDIPINE ADVANTAGES OVER AMLODIPINE

Ø One of the main advantage of CILNIDIPINE is it REDUCES THE INCIDENCE OF PEDAL EDEMA UNLIKE AMLODIPINE

Ø L-type calcium channel blocker (Amlodipine) dilates the only arterioles & not the venules, hence blood pressure increases in the capillary bed and are thought to cause leg edema.

After DPCO-2013, 
348 Drugs are now under DPCO and Amlodipine is one of them,

So, All the Pharmaceutical Formulation Company Searching alternative for Amlodipine, and Cilnidipine is best option of Amlodipine.

Cilnidipine Approved by CDSCO or DCGI on 21-06-2007

Cilnidipine have compatibility with other API like Telmisartan, Olmesartan Medoxomil, Ramipril and Metoprolol Succinate as it found in combination formulation in Indian markets are as follow.

Cilnidipine 5 mg Tablet 
Cilnidipine 10 mg Tablet
Cilnidipine 20 mg Tablet
Cilnidipine 5 mg + Telmisartan 20 mg Tablet
Cilnidipine10 mg + Telmisartan 40 mg Tablet
Cilnidipine 10 mg + Metoprolol Succinate 25 mg Tablet
Cilnidipine 10 mg + Metoprolol Succinate 50 mg Tablet
Cilnidipine 10 mg + Olmesartan Medoxomil 20 mg Tablet
Cilnidipine 10 mg + Olmesartan Medoxomil 40 mg Tablet
Cilnidipine 10 mg + Ramipril IP 10 mg Capsule
Cilnidipine 10 mg + Ramipril IP 2.5 mg Capsule
Cilnidipine 5 mg + Hydrochlorothiazide 12.5 mg + Telmisartan 40 mg










ADDITIONAL INFORMATION

CAS No.
132203-70-4
Min. Order Quantity
1 Kilogram
Port
NhavaSheva By Sea and Sahar Airport By Air
Freight
To Pay basis
Insurance
Your Account
Payment Terms
L/C, T/T
Delivery Time
Immediates
Packaging Details
HDPE drum with inner LPDE liners


SPECIFICATION


Tests
Requirements
Results
Physical appearance
Yellowish or yellow powder
Confirmed
Solubility
Soluble in Dimethyl sulphoxide, Practically insoluble in water, Slightly soluble in anhydrous ethanol
Confirmed
Identification by IR
IR absorption of the sample must be concordant with the standard spectrum.
Confirmed
Melting Point
105°-110°C
107°-109°C
Loss on drying
Not more than 0.50% w/w
0.02%w/w
Residue after Ignition
Not more than 0.20% w/w
0.07%w/w
Heavy metals
Not more than 10 ppm
Less than 10 ppm
Related substances(by    HPLC)
Individual impurity
Total impurities

Not more than 0.5%
Not more than 1.0%

0.20%
0.28%
Assay (on dried base)
Not less than 98.5%
99.4%w/w
Conclusion
The material complies with respect to the above specification


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